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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GLI1 All Species: 24.55
Human Site: S457 Identified Species: 54
UniProt: P08151 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08151 NP_005260.1 1106 117904 S457 S D H S P A G S A A N T D S G
Chimpanzee Pan troglodytes Q5IS56 1580 169881 I720 C S S Q Q S P I S N Y S N S G
Rhesus Macaque Macaca mulatta XP_001116072 1106 117669 S457 S D H S P A G S A A N T D S G
Dog Lupus familis XP_538247 1105 117188 S456 S D H S P A G S A A N T D S G
Cat Felis silvestris
Mouse Mus musculus P47806 1111 118537 S459 S D H S P A G S A A N T D S G
Rat Rattus norvegicus XP_345833 1109 118200 S456 S D H S P A G S A A N T D S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506723 1591 170747 I721 C S S E Q S P I S H Y S N S G
Chicken Gallus gallus P55878 556 60197
Frog Xenopus laevis Q91690 1360 149404 S480 S E R S P L G S T N N N D S G
Zebra Danio Brachydanio rerio NP_840081 1404 152814 S526 S E R S P L G S A N N N D S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P19538 1397 153262 V678 N H H L V N G V R A S D S L L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31.7 96.8 91.1 N.A. 85.5 85.8 N.A. 32.5 33.6 40.5 39.6 N.A. 23.9 N.A. N.A. N.A.
Protein Similarity: 100 42.1 97.6 93.4 N.A. 89.1 89.5 N.A. 42.5 39.4 54.1 51.4 N.A. 37.9 N.A. N.A. N.A.
P-Site Identity: 100 13.3 100 100 N.A. 100 100 N.A. 13.3 0 60 66.6 N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 40 100 100 N.A. 100 100 N.A. 40 0 66.6 73.3 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 46 0 0 55 55 0 0 0 0 0 % A
% Cys: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 46 0 0 0 0 0 0 0 0 0 10 64 0 0 % D
% Glu: 0 19 0 10 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 73 0 0 0 0 0 0 0 82 % G
% His: 0 10 55 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 19 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 10 0 19 0 0 0 0 0 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 10 0 0 0 28 64 19 19 0 0 % N
% Pro: 0 0 0 0 64 0 19 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 19 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 19 0 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 64 19 19 64 0 19 0 64 19 0 10 19 10 82 0 % S
% Thr: 0 0 0 0 0 0 0 0 10 0 0 46 0 0 0 % T
% Val: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _